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NanoFuse Research

Featured Study

sacrix revision of si bone.jpg

Salvage of failed direct lateral sacroiliac joint fixation using a new percutaneous lateral-oblique transfixation technique with two variable-threaded screws: a multicenter case report of three cases

Kingsley R. Chin^, Richard R. Francis, William M. Costigan, Erik Spayde, Chidubem Ike,  Yujin Jeong, Deepak K. Pandey, Jason A. Seale.

This is a clinically valuable report because until now there was no reconstructive surgery to revise direct lateral implants other than removal with potential neurovascular risks. This is the first article to demonstrate a lateral-oblique transfixation technique with two variable-threaded screws for successful salvage of SIJ pseudoarthrosis after direct lateral fixation without implant removal. The Sacrix technique achieved immediate stability and long-term fusion documented on computed tomography (CT) scan as early as  6 months.

CT Scan and Clinical Outcomes of Novel Lateral-Oblique Percutaneous Sacroiliac Joint (SIJ) Fixation: Technique and Literature Review

Kingsley R. Chin^, Fabio J. Pencle, Jason A. Seale, Deepak K. Pandey

This pilot study demonstrated the feasibility and effectiveness of a new percutaneous lateral-oblique SIJ fusion technique with a threaded compression screw done safely in an ASC. Patients demonstrated early pain relief and long-term fusion of their SIJ.

Safety And Efficacy Of A Nano-Bioactive Glass Combined With Demineralized Bone Matrix (DBM) Versus DBM Alone With Standalone PEEK Cages In Single-Level ACDF: A Prospective Randomized Controlled Trial Pilot Study

Kingsley R. Chin^, William M. Costigan, Erik Spayde, Vito Lore, Hope Estevez, Chukwunonso C. Ilogu , Jason A Seale

Our study demonstrated 100% fusion rate.  VAS neck and NDI outcomes improved by 89% and 68% respectively with the use of combination biologic. Signs of fusion were seen as early as 6 weeks with anterior bridging bone

Pending Publication

01

Efficacy of an FDA Approved Synthetic Nano-Bioactive Glass Plus Demineralized Bone Matrix (DBM) Combination versus DBM Alone in Instrumented Lumbar Fusion for Low-Grade Degenerative Spondylolisthesis: A Prospective Randomized Controlled Trial Pilot Study

Pending Publication

02

Comparative Osteoinductive Potential of BMP-2, Bioactive Glass, and Demineralized

Bone Matrix: An In Vitro Alkaline Phosphatase Assay Study

Pending Publication

03

A Prospective Randomized Controlled Trial Comparing Nano-Bioactive Glass plus Demineralized Bone Matrix (DBM) vs. DBM Alone in Single-Level ACDF with Standalone PEEK Cages

Pending Publication

04

An In Vitro Study of Alkaline Phosphatase Induction as a Quantitative Measure of the Osteoinductive Potential of FDA-Approved Nano-Bioactive Glass Combined with Demineralized Bone Matrix (DBM) vs Bioactive Glass Alone and DBM Alone

Pending Publication

NanoFuse Biologics Bioglass Studies

01

Cell Tissue Bank. 2013 Mar;14(1)

Osteoconductivity and osteoinductivity of NanoFUSE(®) DBM

James F Kirk 1, Gregg Ritter, Chad Waters, Sonoko Narisawa, José Luis Millán, James D Talton

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02

International Journal of Biomedical Materials Research. 2015 July;3(3)

Radiographic, Histologic and Mechanical Comparison of NanoFUSE® DBM and a Bioactive Glass in a Rabbit Spinal Fusion Model

James F. Kirk, Gregg Ritter, Michael J. Larson, Robert C. Waters, Isaac finger, John Waters, John H. Abernethy, Dhyana Sankar, James D. Talton, Ronald R. Cobb

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04

Acta Biomater. 2011 Jun;7(6)

Bioactive glass in tissue engineering

Mohamed N Rahaman 1, Delbert E Day, B Sonny Bal, Qiang Fu, Steven B Jung, Lynda F Bonewald, Antoni P Tomsia

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05

J Spine Surg. 2023 Sep 22;9(3)

Salvage of failed direct lateral sacroiliac joint fixation using a new percutaneous lateral-oblique transfixation technique with two variable-threaded screws: a multicenter case report of three cases

Kingsley R Chin , Richard R Francis, William M Costigan, Erik Spayde, Chidubem Ike, Yujin Jeong, Deepak K Pandey, Jason A Seale

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