CLINICAL EVIDENCE

Science-Driven Innovation in Spine Surgery

Quality scientific research proves what works

Featured Research Articles

Recent peer-reviewed publications from our portfolio companies

INSPAN

Prospective 5-year follow-up of L5-S1 versus L4-5 midline decompression and interspinous-interlaminar fixation as a stand-alone treatment for spinal stenosis compared with laminectomies

SACRIX

A prospective multicenter randomized controlled trial on safety and procedural competency in SI joint fusion performed by interventional pain physicians trained by a spine surgeon.

FACETFUSE

A comparative cadaveric biomechanical study of bilateral FacetFuse® transfacet pedicle screws versus bilateral or unilateral pedicle screw-rod construct.

Chin KR, Seale JA, Bruce CA, Yu WD, Anagnost SC, Kushwaha VP, Sung RD, Gabriel J, Meyer CS, Crawford NR, Lore V.

J Spine Surg. 2024 Sep 23;10(3):354-361.

DOI: 10.21037/jss-24-10. Epub 2024 Sep 4.PMID: 39399093

NANOFUSE

Comparative Osteoinductive Potential of BMP-2, Bioactive Glass, and Demineralized Bone Matrix: An In Vitro Alkaline Phosphatase Assay Study

Chin KR, Ilogu CC, Chebrolu S, Costigan WM, Spayde E, Lore V, Beall DP, Lane R, Gabriel JP, Humad A, Seale JA.

Int J Spine Surg. 2025 Dec 28;19(6):652-658

DOI: 10.14444/8841.PMID: 41456902.

AXIOMED

Comparative in Vitro Analysis of Wear Particles Generated by a Viscoelastic Disc Versus 2 Articulating Total Disc Replacements.

Chin KR, Chebrolu S, Sung RD, Carlson JR, McFarland MW, Spayde E, Costigan WM, Thompson S, Lore V, Zimmers KB, Estevez H, Pangarkar S, Humad A, Ilogu CC, Seale JA.

J Bone Joint Surg Am. 2026 Jan 7;108(1):68-74.

DOI: 10.2106/JBJS.25.00594. Epub 2025 Nov 24.PMID: 41284766

AXIOMED

ASTM biomechanical study comparing the AxioMed lumbar viscoelastic disc to human lumbar disc data

Chin KR, Chebrolu S, Sung RD, Carlson JR, McFarland MW, Spayde E, Costigan WM, Thompson S, Lore V, Zimmers KB, Estevez H, Pangarkar S, Humad A, Ilogu CC, Seale JA.

Clin Biomech (Bristol). 2025 Dec;130:106686

DOI: 10.1016/j.clinbiomech.2025.106686. Epub 2025 Oct 22..

AXIOMED